F PAN DSR | Scientific Mechanism & Overview

F PAN DSR is a highly effective, synergistic combination prescription capsule designed for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and non-ulcer dyspepsia where gastric dysmotility is a concurrent factor.

Each hard gelatin capsule contains:

• Pantoprazole Sodium IP (Equivalent to Pantoprazole): 40 mg (As Gastro-Resistant Pellets)

• Domperidone IP: 30 mg (As Prolonged-Release Pellets)

• Approved Colours: Lake of Indigo Carmine & Lake of Sunset Yellow FCF used in capsule shells.

Marketed by FENESTRA PHARMACEUTICALS PVT. LTD. and manufactured by the country’s leading WHO-GMP compliant producer, Pure & Cure Healthcare Pvt. Ltd. (A subsidiary of Akums Drugs & Pharmaceuticals Ltd.), F PAN DSR is produced under stringent quality systems (AN ISO 9001:2015 Certified Company) ensuring uniform therapeutic efficacy and chemical stability.

Key Clinical Features & Indications

• 24-Hour Acid Suppression: Pantoprazole selectively blocks the H+/K+-ATPase enzyme (the proton pump) in gastric parietal cells, significantly lowering basal and stimulated gastric acid output.

• Optimized Gastric Emptying: Domperidone acts as a peripheral dopamine receptor antagonist, increasing lower esophageal sphincter tone and accelerating antroduodenal coordinated motility to actively prevent acid regurgitation.

• Advanced Pellet Technology: The combination of enteric-coated (gastro-resistant) and sustained-release (prolonged-release) pellets inside a single capsule prevents active drug degradation while delivering a steady therapeutic plasma level.

• Mucosal Healing Acceleration: Provides the steady physiological environment necessary to allow inflamed or eroded esophageal mucosa to heal effectively.

Technical & Manufacturing Specifications

• Marketed by: Fenestra Pharmaceuticals Pvt. Ltd., No. 751, 8th Cross, 4th Main, M.C. Layout, Vijaynagar, Bangalore-560040.

• Manufactured at: Pure & Cure Healthcare Pvt. Ltd., Plot No. 26A, 27-30, Sector-8A, I.I.E., SIDCUL, Ranipur, Haridwar-249403, Uttarakhand.

• Manufacturing License Number: 31/UA/2013

• Packaging Configuration: 10 x 10 Capsules standard pharmaceutical carton boxes.

Directions for Use & Storage Guidelines

• Dosage: As directed by the Physician. Typically prescribed as one capsule daily, taken in the morning strictly 30–60 minutes before breakfast.

• Administration Advice: Capsule should be swallowed whole with water. Do not open, chew, or crush the capsule, as doing so destroys the specialized gastro-resistant and prolonged-release coatings of the inner pellets.

• Storage Condition: Store protected from light and moisture at a temperature not exceeding 25°C. Keep all medicines completely out of reach of children.

• Regulatory Classification: SCHEDULE H PRESCRIPTION DRUG – CAUTION: Not to be sold by retail without the prescription of a Registered Medical Practitioner.

FAQs – Frequently Asked Questions

What is F PAN DSR used for?

F PAN DSR is prescribed to treat conditions caused by excess stomach acid coupled with slow digestion, such as Gastroesophageal Reflux Disease (GERD), acid reflux, peptic ulcers, and functional dyspepsia.

Why is F PAN DSR a combination of two different medicines?

It combines Pantoprazole (an acid reducer) with Domperidone (a prokinetic). While Pantoprazole stops the stomach from making too much acid, Domperidone speeds up stomach emptying and moves food through the gut, preventing acid from washing back up into the esophagus.

When is the best time to take F PAN DSR?

For maximum efficacy, it should be taken on an empty stomach, ideally first thing in the morning at least half an hour before breakfast. This allows the proton pump inhibitors to be absorbed before the pumps are fully activated by food.

Can I break or chew the capsule if I have trouble swallowing?

No. The medicine inside consists of specialized enteric-coated gastro-resistant and prolonged-release pellets. Chewing or crushing them destroys these layers, causing the medicine to release all at once in the stomach, which lowers its performance and can increase side effects.